|Premiere Episode||Sweet Baby|
|Premiere Date||April 5th 2012|
|Finale Episode||Grant: For the People|
|Finale Date||May 17th 2012|
- Kerry Washington as Olivia Pope
- Henry Ian Cusick as Stephen Finch
- Columbus Short as Harrison Wright
- Darby Stanchfield as Abby Whelan
- Katie Lowes as Quinn Perkins
- Guillermo Diaz as Huck
- Jeff Perry as Cyrus Beene, White House Chief of Staff
- Tony Goldwyn as Fitzgerald "Fitz" Thomas Grant III - President of the United States (POTUS)
Supporting characters are those who play a bigger part in storylines of the main characters.
- Bellamy Young as First Lady Mellie Grant - First Lady of the United States (FLOTUS)
- Joshua Malina as Assistant US Attorney David Rosen
- Matt Letscher as Billy Chambers - Chief of Staff to the Vice President
- Dan Bucatinsky as James Novak
- Kate Burton as Vice President Sally Langston - Vice President of the United States
- Brian Letscher as Secret Service Agent Tom - assigned to POTUS detail
- Stoney Westmoreland as Secret Service Agent Hal - assigned to POTUS detail
Minor Recurring Cast
- Leslie Grossman as Lisa - DC Coroner
- Troy Winbush as Morris Elcott - Security Guard @ White House Main Gate
This is a list of actors/characters that appear in only one episode of this season, and appear in one or more episodes in future seasons. They are listed in chronological order by episode appearance.
- 1 Returns in Season Two appearing in one episode.
- 2 Returns in Season Two appearing in more than one episode
- 3 Returns in seasons two & three appearing in more than one episode both seasons.
- 4 Returns in all future seasons (2, 3 & 4) appearing in more than one episode each season.
These actors/characters only appeared in this season.
Supporting characters are those who play a bigger part in storylines of the main characters and the overall season storyline.
This is a list of Guest actors/characters that appear in only one episode of the season. They are listed in chronological order by episode appearance.