Assassination and Murders are used throughout Scandal, when a person or an organization needs someone to disappear. This is usually because of leaked information, they know too much information or because the person knows about B613.
- Assassinations are usually ordered by a person in Command or in charge.
- In B613, the orders are given out by either Rowan Pope or Jake Ballard. The orders are given out in the form of "Kill Cards" or formally at a meeting; between Command and an Agent.
- Charlie killed Amanda Tanner - "Crash and Burn"
- Jake Ballard killed Vanessa Chandler, Shelby Moss and James Novak - "Kiss Kiss Bang Bang"
- Tom Larsen was ordered by Eli Pope to assassinate Jerry Grant Jr., Fitz Grant's son. - "Randy, Red, Superfreak and Julia"
- Gus killed Ian Woods when he was fed up of following orders - "Gladiators Don’t Run"
- Huck killed Drug Mob via Maya Lewis aka Marie Wallace - "Gladiators Don’t Run"
- Huck killed Sue Thomas after she wanted to leak her tell-all book - "It's Good to Be Kink"
- Eli Pope was ordered to killed Francisco Vargas in order to save his girlfriend Sandra. - "Extinction"
- Meg was ordered to assassinate Jennifer Fields by Abby Whelan. - "A Traitor Among Us"
- Samantha Ruland murdered Elizabeth North in front of Mellie to threatened her when she refused to work with Peus and Samantha when she becomes President. - "Trojan Horse"