Assassination and Murders are used throughout Scandal, when a person or an organization needs someone to disappear. This is usually because of leaked information, they know too much information or because the person knows about B613.
- Assassinations are usually ordered by a person in Command or in charge.
- In B613, the orders are given out by either Rowan Pope or Jake Ballard. The orders are given out in the form of "Kill Cards" or formally at a meeting; between Command and an Agent.
- Jake Ballard killed Vanessa Chandler, Shelby Moss and James Novak - "Kiss Kiss Bang Bang"
- Tom Larsen was ordered by Eli Pope to assassinate Jerry Grant Jr., Fitz Grant's son - "Randy, Red, Superfreak and Julia"
- Eli Pope was ordered to killed Francisco Vargas in order to save his girlfriend Sandra - "Extinction"
- Meg was ordered to assassinate Jennifer Fields by Abby Whelan - "A Traitor Among Us"
- Verna Thornton hired Becky Flynn to assassinate Fitz Grant and frame Huck for the assassination attempt - "Happy Birthday, Mr. President"
- Charlie killed Amanda Tanner - "Crash and Burn"
- Rowan killed Harrison Wright after he found out that Rowan was planning on killing Fitz Grant's son Jerry Grant Jr. - "Randy, Red, Superfreak and Julia"
- Gus killed Ian Woods when he was fed up of following orders - "Gladiators Don’t Run"
- Huck killed a drug Mob via aka Marie Wallace - "Gladiators Don’t Run"
- Huck killed Sue Thomas after she wanted to leak her tell-all book - "It's Good to Be Kink"
- Jake Ballard killed Franklin Russell after he discovered that Franklin killed Elise Martin and wanted to reinstate B613 - "Baby, It's Cold Outside"
- Olivia Pope killed Andrew Nichols after he wanted to write a tell-all book and said he would kidnap Olivia again - "Thwack!"
- Samantha Ruland murdered Elizabeth North in front of Mellie to threatened her when she refused to work with Peus and Samantha when she becomes President - "Trojan Horse"
- Eli Pope killed Samantha Ruland after escaping The White House - "The Box"
- Quinn Perkins killed Meg after she attempted to kill Huck - "Dead in the Water"
- Jake Ballard killed Theodore Peus when he found him trying to initiate another drone attack on the United States - "Mercy"
- Olivia Pope killed Luna Vargas when she found out that Luna was responsible for hiring Theodore Peus and Samantha Ruland to kill her Husband Francisco Vargas - "Transfer of Power"
- Olivia's assistant Lucy Riccio killed Curtis Pryce after Quinn told Curtis what really happened in the bombing of the plane President Rashad - "Something Borrowed"